dentinoameloblastoma with ghost cells

Dr DC Shetty’s work on Dentinoameloblastoma with ghost cells

According to the various research data, the future of Medical Science is going to be great as new and new research and technology are going on. Dr. Devi Charan Shetty who is Principal of the I.T.S. Dental College, Murad Nagar, Ghaziabad has submitted a case report on Dentinoameloblastoma with ghost cells which emphasize on knowing its biological behavior. He sets an example for our future generation by successfully completing this research paper and also contributed in this field by showing his work. He and his other team members including Kiran Kumar,Vijay Wadhwan, Raghu Dhanapal, Harkanwal Preet Singh done a very good work in this field.

Dr DC Shetty’s case report on Dentinoameloblastoma with ghost cells

The term Ameloblastomas are known as a homogeneous group of neoplasms with locally invasive character which arise from odontogenic epithelium. He aimed to research on this topic because this problem generally do not show induction of dental hard tissue formation other than in some cases and also biological behavior and histogenesis of tumors is still unexplored as there is lack of studies relevant to this topic and long follow‑up of these patients were a challenging task but Dr Devi Charan Shetty completed this report successfully with his dedicated work.

The case study Dr. DC Shetty included in the his work was for the 45‑year‑old female patient who had complained of painless swelling in upper region of jaw and face from past 1 year. The swelling was static in size till the patient got her one of upper tooth extracted due to tooth decay. Cone beam computed tomography (CBCT) evaluation was demonstrated. There is complete loss of bony structures and perforation of buccal and palatal cortical plates with internal flecks of calcifications and resorption of root and other reports like urine examination etc. were found normal.  He observed that Numerous ghost cells lying in close association to epithelium. Also connective tissue stroma is mature showing dense collagen bundles infiltrated and few chronic inflammatory cells seen.

dentinoameloblastoma with ghost cells

Conclusion of Dr. Devi Charan Shetty’s case report

The old report made by Slabbert observed that intimate association of dentinoid like material with odontogenic epithelium in unicystic neoplasm which contains typical follicles of ameloblastoma along with psammomatous‑type dystrophic calcifications in a male patient of Asian ethnic origin on which athis case study was done. While in the Dr. DC Shetty report shows the plexiform ameloblastoma along with large number of dentinoid/osteodentin‑like material withl unique presence of ghost cells. He feel that dentinoameloblastoma forms an unsimiliar stage of odontoameloblastoma as well as currently accepted thoughts on tooth embryogenesis also suggest that enamel formation can  occur only subsequent to induction of ameloblasts by dentin.  ameloblastomas in general terms regarded as a homogeneous group of neoplasms and also detailed investigations proves clinicopathological diversity in a unique number of tumors. Many of the changes emphasize on the differentiation potential of neoplastic odontogenic epithelium and add fascinating parameters to the study of tissue reactions related with this common odontogenic tumor. Further case reports of Dr. Shetty on dentinoameloblastomas are expected to emphasise on the biological behavior and nature of this unique tumor.

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